NeurosciencebioRxivPreprint
Disabling Gβγ SNARE interaction in transgenic mice disrupts GPCR-mediated presynaptic inhibition leading to physiological and behavioral phenotypes.
Zack Zurawski, Analisa D. Thompson Gray, Lillian J. Brady…·Heidi E. Hamm
This study shows that disrupting Gβγ-SNARE interaction in mice leads to impaired gait, nociception, and hippocampal function, highlighting its role in GPCR-mediated presynaptic inhibition.
5 citations