Emily Church

Synaptic integration of subquantal neurotransmission by co-localized G protein coupled receptors in presynaptic terminals

This paper investigates how two co-localized G protein-coupled receptors, GABAB and 5-HT1B, differentially modulate synaptic transmission in presynaptic terminals through distinct mechanisms.

Quantitation of single action potential-evoked Ca2+ signals in CA1 pyramidal neuron presynaptic terminals

The paper quantifies single action potential-evoked Ca2+ signals in CA1 pyramidal neuron presynaptic terminals and models their dynamics and interactions.

Disabling Gβγ SNARE interaction in transgenic mice disrupts GPCR-mediated presynaptic inhibition leading to physiological and behavioral phenotypes.

This study shows that disrupting Gβγ-SNARE interaction in mice leads to impaired gait, nociception, and hippocampal function, highlighting its role in GPCR-mediated presynaptic inhibition.