Adjuvants MPLA and SMNP induce antiviral immunity and indirectly revert HIV-1 latency
Jade Jansen, Killian E. Vlaming, Leanne C. Helgers…·Neeltje A. Kootstra
This study shows that SMNP, a TLR4-targeted adjuvant, induces stronger immune activation and reduces HIV-1 reservoir size in PWH ex vivo compared to MPLA.