ImmunologyNature CommunicationsPeer-reviewed
The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection
Sophie Desgraupes, Adrien Decorsière, Suzon Perrin…·Nathalie Jane Arhel
This study shows that RANBP2 mutations impair its nuclear envelope localization, leading to increased influenza replication and pro-inflammatory cytokine production.
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