Adam Knapp

Generalized Maternal-Paternal Genotype Markov Model for Single-Cell Lineages

The paper develops a generalized maternal-paternal genotype Markov model for diploid DNA, exploring its mathematical formulations and comparing it to existing unphased models.

Personalizing computational models to construct medical digital twins

This paper develops an algorithm to calibrate agent-based computational models to individual patients using data assimilation techniques for personalized medicine.

SteadyCellPhenotype: A web-based tool for the modeling of biological networks with ternary logic

SteadyCellPhenotype models ternary biological networks by finding steady states and simulating trajectories with visualization tools.

Multiscale mechanistic modelling of the host defense in invasiveaspergillosis reveals leukocyte activation and iron acquisition as driversof infection outcome

This study develops a multiscale computational model of invasive aspergillosis to identify key factors determining infection outcome, finding that fungal growth, iron acquisition, and leukocyte activation are critical.