Luis Sordo Vieira

The heme-scavenger, hemopexin, protects against fungal lung injury by mitigating NETosis: an experimental and computational study.

This study shows hemopexin reduces fungal lung injury by limiting heme-mediated NETosis in aspergillosis.

SteadyCellPhenotype: A web-based tool for the modeling of biological networks with ternary logic

SteadyCellPhenotype models ternary biological networks by finding steady states and simulating trajectories with visualization tools.

Multiscale mechanistic modelling of the host defense in invasiveaspergillosis reveals leukocyte activation and iron acquisition as driversof infection outcome

This study develops a multiscale computational model of invasive aspergillosis to identify key factors determining infection outcome, finding that fungal growth, iron acquisition, and leukocyte activation are critical.

Control of Intracellular Molecular Networks Using Algebraic Methods

This paper introduces a control method for multistate biological networks using algebraic techniques and applies it to cancer and iron metabolism models to identify intervention strategies.

Computing Signal Transduction in signaling networks modeled as Boolean Networks, Petri Nets and hypergraphs

The paper compares formalisms for modeling signal transduction in networks and introduces a new approach using topological factories.