Author

Hongmei Yin

Shenzhen Bay LaboratoryORCID 0000-0002-5724-0326Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein design· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:graph neural network· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Jian ZhaniD· 2 shared Yaoqi ZhouiD· 2 shared Chao ZhangiD· 1 shared Fei Ling· 1 shared Jianxun QiiD· 1 shared Jinle TangiD· 1 shared John Z. H. ZhangiD· 1 shared Ke CheniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Jian ZhanORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 4, 2025

Designing a broad-spectrum four-helix bundle targeting different strains of SARS-CoV-2 Spike Receptor Binding Domains with ACE2-like binding interface

Qinghui Nie, Hongmei Yin, Ke Chen…·Yaoqi Zhou

The paper designs a protein that binds to multiple SARS-CoV-2 RBD variants with high affinity, demonstrating a strategy for broad-spectrum antiviral inhibitors.

DOI 10.1101/2025.06.04.657798

humanproteomics

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedDec 7, 2023

SPIN-CGNN: Improved fixed backbone protein design with contact map-based graph construction and contact graph neural network

Xing Ming Zhang, Hongmei Yin, Fei Ling…·Yaoqi Zhou

This paper introduces SPIN-CGNN, a protein design method using contact maps and graph neural networks, showing improved sequence recovery and structural accuracy compared to existing methods.

15 citations

protein structuregraph neural network

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