Jinle Tang

Designing a broad-spectrum four-helix bundle targeting different strains of SARS-CoV-2 Spike Receptor Binding Domains with ACE2-like binding interface

The paper designs a protein that binds to multiple SARS-CoV-2 RBD variants with high affinity, demonstrating a strategy for broad-spectrum antiviral inhibitors.

RNA-MobiSeq: Deep mutational scanning and mobility-based selection for RNA structure inference

The paper introduces MobiSeq, a method combining deep mutational scanning and mobility-based selection to predict RNA tertiary structures by analyzing covariational signals and improving energy-based predictions.

Effective High-Accuracy Prediction of Protein Structures from Easily Obtainable Artificial Homologous Sequences by Structure-Stability-Based Selection

The paper shows that using artificially generated, structure-stability-selected homologous sequences improves AlphaFold2's accuracy for protein structure prediction, achieving better than 2 Å RMSD for most tested proteins.