BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
2.6-A resolution cryo-EM structure of a class Ia ribonucleotide reductase trapped with mechanism-based inhibitor N3CDP
Dana Emily Westmoreland, Patrícia R. Feliciano, Gyunghoon Kang…·Catherine Luschinsky Drennan
This paper presents a 2.6-A resolution cryo-EM structure of E. coli class Ia RNR trapped with inhibitor N3CDP, revealing details of radical transfer and PCET mechanism.