Catherine Luschinsky Drennan

The paper identifies a second-sphere threonine residue that directs iron-oxygen species in an Fe(II)/α-ketoglutarate-dependent isonitrile synthase, revealing its role in catalytic regulation.

This paper determines the structure of indoleacetate decarboxylase and challenges the proposed mechanism of skatole formation by showing it may follow a Kolbe-type decarboxylation rather than hydrogen atom transfer.

This paper presents a 2.6-A resolution cryo-EM structure of E. coli class Ia RNR trapped with inhibitor N3CDP, revealing details of radical transfer and PCET mechanism.