A conserved epilepsy-associated gene co-expression module identifies increased metabolic rate as a shared pathomechanism
Jingyi Long, Spencer G. Jones, Ana Serna, Boyd van Reijmersdal, Franziska Kampshoff, Sara Aibar, Patrik Verstreken, Martijn A. Huynen, Kevin Lüthy, Mireia Coll-Tané, Annette Schenck
The paper identifies a conserved gene co-expression module in Drosophila linked to epilepsy, showing metabolic rate and AMPK activity influence seizure susceptibility.
Disease Models & Mechanisms · May 22, 2025Peer-reviewedNeuroscience