NeuroscienceiSciencePeer-reviewed
Excessive activation of the RAS/MAPK pathway triggers adult-onset motor axonal degeneration
Marije Been, Erwan Lambert, Ana Serna…·Erik Storkebaum
This study identifies excessive RAS/MAPK pathway activation as a cause of adult-onset motor axonal degeneration in Drosophila, showing that inhibiting the pathway can rescue neurodegenerative phenotypes.
DOI 10.1016/j.isci.2026.117507