Author

María Luque

Innsbruck Medical UniversityORCID 0000-0002-5749-1336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Antonio Heras‐GarviniD· 1 shared Charles Anthony DinarelloiD· 1 shared Damaris B. Skouras· 1 shared Jesús Amo‐AparicioiD· 1 shared Kelvin C. LukiD· 1 shared Magdalena Matic· 1 shared Michael KhaliliD· 1 shared Michaela Tanja HaindliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Antonio Heras‐GarvinORCID

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1 paper

Recent·Most cited

NeuroscienceJournal of NeuroinflammationPeer-reviewedJan 31, 2026

Pharmacologic NLRP3 Inhibition Modulates Parkinson's Disease-Associated Microglial Transcriptomic Signatures and Mitigates α-Synuclein-Triggered Neurodegeneration

María Luque, Magdalena Matic, Antonio Heras‐Garvin…·Nadia Stefanova

This study evaluates dapansutrile, an NLRP3 inhibitor, in preclinical models of Parkinson's disease and multiple system atrophy, showing improved motor function, reduced neurodegeneration, and transcriptomic changes in microglia.

9 citationstop 1%

mousebulk RNA-seq

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