Fionna E. Loughlin

dirCLIP uses nanopore sequencing to profile variant-specific RNA-protein interactions, revealing isoform-selective binding and co-occurring sites with high concordance to short-read data.

This study investigates how double serine phosphorylation in TIA-1 affects its phase separation and structure, revealing its role in stress granule formation and disease-related mutations.

This study determines the solution structure of DND1 bound to AU-rich RNA, revealing a novel tandem RRM-RNA recognition mechanism essential for mRNA regulation.