Author

Francisco Fontenla-Iglesias

Emory UniversityORCID 0000-0002-5760-5102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Approach:comparative / phylogenetic analysis· 1 Approach:deep learning· 1 Organism:multiple species· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

Jonathan P. RastiD· 2 shared Max D. CooperiD· 2 shared Sabyasachi DasiD· 2 shared Amelia G. Williams· 1 shared Byron B. Au‐YeungiD· 1 shared C Y Lee· 1 shared Jean‐Louis BoulayiD· 1 shared Jesús LamasiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Jonathan P. RastORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 6, 2026

Ancient IL-6-STAT5 signaling orchestrates inflammation in jawless vertebrates

Francisco Fontenla-Iglesias, Jean‐Louis Boulay, Jonathan P. Rast…·Sabyasachi Das

This study identifies IL-6-like genes in jawless vertebrates and shows their role in inflammation through STAT5 signaling and SOCS gene regulation.

DOI 10.64898/2026.04.02.716188

multiple speciescomparative / phylogenetic analysis

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 17, 2025

An ancient evolutionary origin for IL-1 cytokines as mediators of immunity

Francisco Fontenla-Iglesias, Tse-Mao Lin, Amelia G. Williams…·Sebastian D. Fugmann

This study identifies an ancient evolutionary origin of IL-1 cytokines in invertebrates, showing they share key features with mammalian IL-1 proteins and suggest a foundational role in animal immunity.

1 citation

non-human primateproteomics

𝕏 PostBluesky