Author

Sabyasachi Das

Emory UniversityORCID 0000-0002-9116-9623Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Sabyasachi Das2 papers · Harvard University

Biology Disciplines

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Immunology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:multiple species· 2 Organism:non-human primate· 2 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Jonathan P. RastiD· 3 shared Max D. CooperiD· 3 shared Francisco Fontenla-IglesiasiD· 2 shared Masayuki HiranoiD· 2 shared Alan J. S. BeavaniD· 1 shared Alex de MendozaiD· 1 shared Amelia G. Williams· 1 shared Bastian FrommiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

Jonathan P. RastORCID

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3 papers

Recent·Most cited

Ancient IL-6-STAT5 signaling orchestrates inflammation in jawless vertebrates

Francisco Fontenla-Iglesias, Jean‐Louis Boulay, Jonathan P. Rast, Masayuki Hirano, Byron B. Au‐Yeung, Jesús Lamas, Weiming Li, Thomas L. J. Boehm, Max D. Cooper, Sabyasachi Das

This study identifies IL-6-like genes in jawless vertebrates and shows their role in inflammation through STAT5 signaling and SOCS gene regulation.

bioRxiv · Apr 6, 2026 · PreprintImmunology

An ancient evolutionary origin for IL-1 cytokines as mediators of immunity

Francisco Fontenla-Iglesias, Tse-Mao Lin, Amelia G. Williams, Sabyasachi Das, C Y Lee, Jonathan P. Rast, Max D. Cooper, Katherine M. Buckley, Sebastian D. Fugmann

This study identifies an ancient evolutionary origin of IL-1 cytokines in invertebrates, showing they share key features with mammalian IL-1 proteins and suggest a foundational role in animal immunity.

bioRxiv · Jul 17, 2025 · PreprintImmunology

Hagfish genome illuminates vertebrate whole genome duplications and their evolutionary consequences

Daqi Yu, Yandong Ren, Masahiro Uesaka, Alan J. S. Beavan, Matthieu Muffato, Jieyu Shen, Yongxin Li, Iori Sato, Wenting Wan, James Clark, Joseph N. Keating, Emily M. Carlisle, Richard P. Dearden, Sam Giles, Emma Randle, , Juan Pascual‐Anaya

Chromosome-scale inshore hagfish genome places 1R before the cyclostome-gnathostome split and 2R in the gnathostome stem, and reveals two cyclostome-specific duplications (CR1, CR2).

Nature Ecology & Evolution · Jan 12, 2024Peer-reviewedGenomics✦ In-depth digest