Sourya Bhattacharyya

EpiExpr predicts gene expression using epigenetic data and chromatin interactions, achieving performance comparable to sequence-based models without requiring sequence embeddings.

DiffHiChIP identifies differential chromatin contacts from HiChIP data by addressing limitations in existing methods through improved statistical modeling and distance correction.

Loop Catalog compiles HiChIP data from 1000+ human and mouse samples to provide a resource for analyzing chromatin loops and their regulatory roles.

The paper shows NSD2 overexpression alters chromatin structure and gene expression by affecting CTCF and H3K27ac in specific chromatin domains.

FitHiChIP identifies significant chromatin contacts from HiChIP data by modeling coverage and distance scaling, validating enhancer interactions, and enabling differential contact analysis between immune cell types.