Author

Vivek Kumar Chandra

La Jolla Institute for ImmunologyORCID 0000-0002-4047-015XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:simulation· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Cornelis MurreiD· 1 shared Ferhat AyiD· 1 shared Frank AlberiD· 1 shared Ke Qin GongiD· 1 shared Mark P. Kamps· 1 shared Matthew Denholtz· 1 shared Pandurangan VijayanandiD· 1 shared Sourya BhattacharyyaiD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperMolecular Biology

Cornelis MurreORCID

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2 papers

Recent·Most cited

FitHiChIP: Identification of significant chromatin contacts from HiChIP data

Sourya Bhattacharyya, Vivek Kumar Chandra, Pandurangan Vijayanand, Ferhat Ay

FitHiChIP identifies significant chromatin contacts from HiChIP data by modeling coverage and distance scaling, validating enhancer interactions, and enabling differential contact analysis between immune cell types.

Nature Communications · Sep 17, 2019Peer-reviewedBioinformatics

Comprehensive characterization of neutrophil genome topology

Yina Zhu, Ke Qin Gong, Matthew Denholtz, Vivek Kumar Chandra, Mark P. Kamps, Frank Alber, Cornelis Murre

This study characterizes the genome topology of neutrophils, revealing super-contraction and chromatin reorganization during differentiation.

bioRxiv · Jan 15, 2017Molecular Biology