BioinformaticsbioRxivPreprint
A Falsifiable Framework for Testing Neutralityin T-Cell Receptor Repertoire Databases
Roberto Navarro Quiroz, Andrea Jaruffe Pinilla, Katherine Escorcia…·Elkin Navarro Quiroz
The paper introduces a falsifiable framework to test neutrality in TCR repertoire databases using a biologically calibrated null model, revealing public clonotype patterns inconsistent with neutral drift.
DOI 10.64898/2025.12.04.692300