Author

Kun Chan Zheng

Shanghai Jiao Tong UniversityORCID 0000-0002-5779-6682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Kai NiiD· 2 shared Xiaoyong HuiD· 2 shared Youlong HaiiD· 2 shared Guanggai Xia· 1 shared Honglin JiniD· 1 shared Hongqi CheniD· 1 shared Jianwen Huang· 1 shared Jie MaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Kai NiORCID

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2 papers

Recent·Most cited

LSH-mediated resolution of R-loops mitigates transcription-replication conflicts to preserve genomic stability in prostate cancer cells

Kai Ni, Yu Zhang, Kun Chan Zheng, Jianwen Huang, Nuorong Xiong, Rong Liang, Yingxiao Chen, Honglin Jin, Youlong Hai, Li Wang, Jie Ma, Ranxing Yang, Guanggai Xia, Yueqing Bai, Lujie Song, , Qiang Fu

This study shows LSH resolves R-loops in prostate cancer cells, reducing transcription-replication conflicts and DNA damage, and identifies LSH as a potential therapeutic target.

bioRxiv · Jun 4, 2025 · PreprintCancer Biology

Three Conserved Immune Dysfunction and Exclusion Subtypes in Bladder and Pan-cancers: Prognostic and Immunotherapeutic Significance

Kun Chan Zheng, Youlong Hai, Hongqi Chen, Yukun Zhang, Xiaoyong Hu, Kai Ni

This paper identifies three TIDE subtypes in bladder and pan-cancers, showing their prognostic and immunotherapeutic significance through transcriptome analysis and validation with real-world samples.

Journal of Translational Medicine · Apr 17, 2024Peer-reviewedBioinformatics