Cell BiologybioRxivPreprint
α-Synuclein acts as a cholesteryl-ester sensor on lipid droplets regulating organelle size and abundance.
Reeba Susan Jacob, Alessandro Dema, Hélène Chérot…·Philipp Selenko
This study shows α-Synuclein binds lipid droplets, senses cholesteryl-ester, regulates organelle size and abundance, and links its dysfunction to neurodegenerative diseases.
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