Qian‐Quan Sun

The paper compares gene co-expression networks between mouse and human frontal cortex at single-cell resolution, finding modest gene partner similarity but strong module conservation and no species-specific disease gene partner differences.

The paper introduces the NeuroHab, a low-cost, open-source operant system for high-fidelity behavioral experiments with precise timing and integration with neural recording tools.

The paper constructs a human-specific prefrontal circuit model using transcriptomic data, revealing divergent oscillatory dynamics and highlighting the need for human-specific recalibration of conductance parameters.

This paper introduces the Persistence Spectrum (PERCS) framework to quantify behavioral persistence in mice, revealing that unrewarded effort drives persistence and identifying distinct persistence dimensions across operant tasks.

This study investigates cortical circuit dynamics in Ank3-1b-/- mice, showing disrupted excitatory-inhibitory balance and altered sensory processing, while some sensory functions remain preserved.

The paper shows that SST-INs and PV-INs in the somatosensory cortex differentially regulate predictive actions and emotional responses during trace eyeblink conditioning.

The paper identifies a neural mechanism in the dorsal mPFC motor cortex that initiates persistent movement by selectively encoding contextual information.

The paper investigates how divergent frontal circuits control behavioral uncertainty by analyzing neural representations and behavioral outcomes in an unpredictable environment.

The paper identifies synaptic reorganization in a mouse model of focal cortical malformation and shows that optogenetic stimulation of somatostatin interneurons can stop seizures.