Oshri Avraham

The paper constructs a single-cell atlas of peripheral glia, identifies progenitor-like states, and shows their role in injury response and development.

The paper constructs a single-cell atlas of dorsal root ganglion remodeling after nerve injury and compares interventions to identify glial and immune programs associated with pain and regeneration.

The paper shows that macrophage depletion prevents axon degeneration in bortezomib-induced neuropathy by restoring the DRG microenvironment and reducing inflammation and ECM dysregulation.

Inhibition of endothelin B receptor improves axon regeneration and reverses age-related decline in sensory neurons.

The paper characterizes the transcriptional profile of Satellite Glial Cells (SGC) in mouse, rat, and human at the single-cell level, finding conserved key features across species.

This study compares the DRG microenvironment's response to peripheral and central axon injuries using single-cell profiling, identifying PPAR pathway activation in satellite glial cells as critical for peripheral regeneration.

This study shows that spinal cord injury (SCI) in dorsal column sensory neurons leads to downregulation of lipid metabolism genes, unlike sciatic nerve injury, which may hinder axon regeneration.

This study identifies fatty acid synthesis in satellite glial cells as a mechanism promoting axon regeneration after nerve injury.