Yuanhao Yang

This study investigates clozapine-induced neutropenia in treatment-resistant schizophrenia using single nucleus RNA sequencing to identify cell type-specific transcriptional changes and cell-cell communication patterns.

Targeting GPR183 reduced lung fibrosis and inflammation in a preclinical model, supporting GPR183 as a promising new therapy.

This study shows that CEP55 promotes tumorigenesis in cancer models and its deletion suppresses tumor growth and improves survival, especially in PTEN-deficient cancers.

The paper investigates C4 genetic structural variations in multiple sclerosis, finding associations with disease risk and progression, and links them to immune cell expression and pathways.

The paper identifies genetic associations between diabetes medications and ECG features, finding a causal link between medication use and reduced T-wave area in lead aVR, increasing risk of ischemic heart disease and coronary atherosclerosis.

This study investigates genetic correlations and causal relationships between multiple sclerosis and inflammatory bowel diseases, identifying shared SNPs and tissue-specific heritability patterns.

This study uses Mendelian randomization to show a causal link between type 2 diabetes and cataract risk in East Asians, identifying two candidate genes involved in this relationship.

The paper quantifies assortative mating on complex traits by analyzing SNP data from 400,000 individuals, finding significant evidence for height and educational attainment.