NeurosciencebioRxivPreprint
Exogenous Nav1.1 activity in excitatory and inhibitory neurons reverts Dravet syndrome comorbidities when delivered post-symptom onset in mice with Dravet
Saja Fadila, Bertrand Beucher, Iria G. Dopeso‐Reyes…·Moran Rubinstein
This study shows that delivering a modified SCN1A gene via viral vectors to DS mice improves survival, reduces seizures, and corrects brain activity after symptom onset.
DOI 10.1101/2022.06.10.495591