Systems BiologyPLoS BiologyPeer-reviewed
Non-latching positive feedback enables robust bimodality by de-coupling expression noise from the mean
Brandon S. Razooky, Youfang Cao, Maike M. K. Hansen…·Leor S. Weinberger
The paper investigates how HIV's Tat protein generates bimodal expression through non-latching positive feedback, decoupling noise from mean expression to maintain stochastic bimodality.
21 citations