Detection of astrocyte epigenetic memory in in vitro systems, experimental autoimmune encephalomyelitis and multiple sclerosis samples
Hong‐Gyun Lee, Zhaorong Li, Camilo Faust Akl, Joon-Hyuk Lee, Gavin Piester, Jack Perry Antel, Veit Rothhammer, Michael A. Wheeler, Alexandre Prat, Iain C. Clark, Francisco Javier Quintana
The paper rebuts claims that astrocyte epigenetic memory is due to immune cell contamination, showing its existence in pure astrocyte cultures and MS samples.
bioRxiv · May 30, 2025 · PreprintNeuroscience