Cytokine-mediated activation of exhausted T cells
Eva Goljat, Rahel Daetwyler, Nima Yassini, Nikolas Rakebrandt, Zhaorong Li, Francisco Javier Quintana, Nicole Joller
This study shows that exhausted CD8 T cells can produce IFN-gamma in response to IL-12 and IL-18, indicating retained cytokine-driven effector capacity.
bioRxiv · Oct 3, 2026 · PreprintImmunology