Author
University of ChicagoORCID 0000-0002-5893-9315Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Daniel A. Snellings, Romuald Girard, Rhonda Lightle…·Douglas A. Marchuk
The paper identifies PIK3CA mutations in developmental venous anomalies (DVA) and CCM, showing DVA act as a genetic primer for CCM through shared mutations.
Miguel Alejandro Lopez‐Ramirez, Shady Ibrahim Soliman, Preston Hale…·Mark H. Ginsberg
The paper shows that astrocytes contribute to cerebral cavernous malformations (CCMs) through VEGF production driven by endothelial NO, highlighting non-cell-autonomous mechanisms.
Matthew R. Detter, Robert Shenkar, Christian R. Benavides…·Douglas A. Marchuk
This paper develops new mouse models of cerebral cavernous malformations (CCMs) to better study drug therapies for CCM formation and hemorrhage.