Author

David S. Shames

GenentechORCID 0000-0002-5900-1177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Barzin Y. NabetiD· 1 shared Benjamin B. MorrisiD· 1 shared Carl Michael GayiD· 1 shared Catherine Allison StewartiD· 1 shared Darren R. TysoniD· 1 shared Edurne ArriolaiD· 1 shared Jing WangiD· 1 shared John Victor HeymachiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Barzin Y. NabetORCID

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1 paper

Recent·Most cited

Cancer BiologyMolecular CancerPeer-reviewedMar 20, 2025

DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer

Benjamin B. Morris, Simon Heeke, Yuanxin Xi…·Lauren A. Byers

This study identifies three distinct DDR phenotypes in SCLC associated with chemotherapy response and tumor evolution.

9 citations

humanbulk RNA-seq

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