Author

Barzin Y. Nabet

GenentechORCID 0000-0002-4824-3533Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Myung Chang LeeiD· 2 shared Adrian B. RothiD· 1 shared Alec E. DallasiD· 1 shared Alexandros P. DrainasiD· 1 shared Armin Braun· 1 shared Axel DucretiD· 1 shared Benjamin B. MorrisiD· 1 shared Bilgenaz StolliD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Myung Chang LeeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

T CELLS promote the growth of small-cell lung carcinoma via an IL-6/CD74 axis

Maya Baron, Zoé Ginestet, Debadrita Bhattacharya, Myung Chang Lee, Alexandros P. Drainas, Clara L. Poupault, Yoko Nishiga, Alec E. Dallas, Barzin Y. Nabet, Julien Sage

The paper shows T cells promote SCLC growth through an IL-6/CD74 axis, and IL-6 blockade enhances immunotherapy effectiveness in SCLC.

bioRxiv · Dec 21, 2025 · PreprintCancer Biology

DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer

Benjamin B. Morris, Simon Heeke, Yuanxin Xi, Lixia Diao, Qi Wang, Pedro Rocha, Edurne Arriola, Myung Chang Lee, Darren R. Tyson, Kyle Concannon, Kavya Ramkumar, Catherine Allison Stewart, Robert J. Cardnell, Runsheng Wang, Vito Quaranta, , Lauren A. Byers

This study identifies three distinct DDR phenotypes in SCLC associated with chemotherapy response and tumor evolution.

Molecular Cancer · Mar 20, 2025Peer-reviewedCancer Biology

Human Lung Alveolar Model with an Autologous Innate and Adaptive Immune Compartment

Linda Steinacher, Bruno Gjeta, Marisa Pimentel Mendes, Floriana Cremasco, Irineja Cubela, Marina Bellavista, Laura Gaspa-Toneu, Luisa Lauer, Qianhui Yu, Ryo Okuda, Barzin Y. Nabet, Velimir Gayevskiy, Michel Siegel, Axel Ducret, Evodie Lassalle, , Lauriane Cabon

This paper develops human lung alveolar immuno-organoids with autologous immune cells to model immune-epithelial interactions and study inflammation-related pulmonary side effects.

bioRxiv · Feb 27, 2025 · PreprintCell Biology