Author

Sin Lih Tan

AstraZeneca (United Kingdom)ORCID 0000-0002-5911-0832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aatman S. DoshiiD· 1 shared Aparna GorthiiD· 1 shared Deanna A. MeleiD· 1 shared Elizabeth S. JaenschiD· 1 shared Gayathri BommakantiiD· 1 shared Iswarya Karapa Reddy· 1 shared James H. KurasawaiD· 1 shared Jason Daniel BuenrostroiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Aatman S. DoshiORCID

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintFeb 22, 2024

Degradation of IKAROS prevents epigenetic progression of T cell exhaustion in a novel antigen-specific assay

Tristan Tay, Gayathri Bommakanti, Elizabeth S. Jaensch…·Deanna A. Mele

The paper develops an antigen-specific assay for T cell exhaustion and identifies IKAROS as a driver of exhaustion, showing that iberdomide prevents exhaustion by blocking chromatin remodeling.

3 citations

humanbulk RNA-seq

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