Author

Xingbo Long

Beth Israel Deaconess Medical CenterORCID 0000-0002-5918-687XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Aria F. OlumiiD· 2 shared Boqing GuiD· 2 shared Christina Sharkey· 2 shared Yaoliang TangiD· 2 shared Zongwei WangiD· 2 shared Aaron FleishmaniD· 1 shared Boris GershmaniD· 1 shared Dandan TaniD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPathology

Aria F. OlumiORCID

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3 papers

Recent·Most cited

NeuroscienceeLifePeer-reviewedSep 17, 2025

A Novel Mouse Model for LAMA2-Related Muscular Dystrophy: Analysis of Molecular Pathogenesis and Clinical Phenotype

Dandan Tan, Yidan Liu, Huaxia Luo…·Hui Xiong

This study presents a Lama2 knockout mouse model for LAMA2-related muscular dystrophy, analyzing its phenotype, neuropathology, and transcriptomics data to elucidate molecular pathogenesis.

1 citation

mousescRNA-seq

𝕏 PostBluesky

PathologyAmerican Journal Of PathologyPeer-reviewedSep 13, 2025

Stromal SRD5A2 promotes prostate growth through WNT5A-LEF1-IGF1 signaling in benign prostatic hyperplasia

Christina Sharkey, Boqing Gu, Xingbo Long…·Zongwei Wang

This study shows SRD5A2 promotes prostate growth via WNT5A-LEF1-IGF1 signaling in BPH, independent of androgen levels.

7 citationstop 3%

humanbulk RNA-seq

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PathologybioRxivPreprintSep 8, 2025

Stem-like Prostate Remodeling in Obesity Mediates Resistance to 5α-Reductase Inhibition Therapy in BPH

Xingbo Long, Christina Sharkey, Rongbin Ge…·Aria F. Olumi

This study shows that obesity-induced stem-like prostate remodeling reduces 5α-reductase inhibitor effectiveness in BPH, and combining weight control with therapy improves outcomes.

DOI 10.1101/2025.09.08.674969

mousehuman

𝕏 PostBluesky