Author

Lachlan E. McInnes

The University of Melbourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Anthony Robert WhiteiD· 2 shared Jeffrey R. LiddelliD· 2 shared Paul S. DonnellyiD· 2 shared Ashley Ian BushiD· 1 shared Bence T. PauliD· 1 shared Benjamin Guy TristiD· 1 shared Blaine Russell RobertsiD· 1 shared Catriona McLeaniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Anthony Robert WhiteORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A patient-derived blood-brain barrier model for screening copper bis(thiosemicarbazone) complexes as potential therapeutics in Alzheimer's disease

Joanna Marta Wasielewska, Kathryn Szostak, Lachlan E. McInnes, Hazel Quek, Juliana C.S. Chaves, Jeffrey R. Liddell, Jari Koıstınaho, Lotta E. Oikari, Paul S. Donnelly, Anthony Robert White

This paper develops a patient-derived BBB model to screen copper bis(thiosemicarbazone) complexes for Alzheimer's disease treatment, identifying CuII(dtsm) as a promising candidate with improved BBB permeability and anti-inflammatory effects.

ACS Chemical Neuroscience · Mar 13, 2024Peer-reviewedNeuroscience

Microglial ferroptotic stress causes non-cell autonomous neuronal death

Jeffrey R. Liddell, James B. W. Hilton, Kai Kysenius, Sara Nikseresht, Lachlan E. McInnes, Dominic James Hare, Bence T. Paul, Benjamin Guy Trist, Kay L. Double, Stephen W. Mercer, Scott Ayton, Blaine Russell Roberts, Joseph S. Beckman, Catriona McLean, Anthony Robert White, , Peter John Crouch

This study shows that microglial ferroptotic stress leads to non-cell autonomous neuronal death in ALS, with a novel inhibitor reducing neurotoxicity.

Molecular Neurodegeneration · Feb 5, 2024Peer-reviewedNeuroscience