Loss of piR-hsa-7221 regulation drives the expression of the LINE1-derived oncogenic lncRNA CASC9 in testicular cancer.
Ahmad Zyoud, Ryan P Cardenas, Nabeelah Almalki, Tinyiko K. Modikoane, Mohammed Ageeli Hakami, Mansour Abdulaziz Alsaleem, Cristina Tufarelli, Nigel Patrick Mongan, Cinzia Allegrucci
This study identifies piR-hsa-7221 as a regulator of the oncogenic lncRNA CASC9 in testicular cancer, showing its loss drives CASC9 expression and promotes cancer progression.
bioRxiv · Feb 17, 2026 · PreprintCancer Biology