Mohammad Umer Sharif Shohan

This paper develops bi-specific CAR-iNKT cells targeting CD19 and CD133 for KMT2A-rearranged leukemia, showing superior efficacy over CAR-T in eradicating leptomeningeal disease and inducing remission.

The paper investigates reproducibility of systems biology models, finding that 49% of 455 models could not be reproduced due to missing data or inconsistencies.

This study designs 8 siRNA molecules targeting SARS-CoV-2's nucleocapsid phosphoprotein and surface glycoprotein genes using sequence conservation and thermodynamic properties.

This study uses molecular docking to evaluate the anti-TB potential of alkaloid compounds against three Mycobacterium tuberculosis proteins, identifying promising candidates with high binding affinity.

This study uses genomic and proteomic data to analyze gene regulatory networks in breast cancer, identifying key genes and pathways involved in disease development and suggesting potential drug targets.