Genetic variants drive altered epigenetic regulation of endotoxin tolerance in BTBR macrophages
Annie Vogel Ciernia, Verena M. Link, Milo Careaga, Janine M. LaSalle, Paul Ashwood
The paper shows BTBR mouse genetic variants lead to altered chromatin accessibility and hyper-responsive innate immunity in macrophages, linking genetic differences to ASD-related immune abnormalities.
Brain Behavior and Immunity · May 23, 2020Peer-reviewedMolecular Biology