Dipjyoti Das

Impact of competition between precursor and mature microRNAs on stochastic gene expression

The paper investigates how competition between precursor and mature microRNAs affects stochastic gene expression in feedback loops, showing noise-induced bimodality outside deterministic bifurcation regions.

Modeling collective cell migration in a heterogeneous environment: Drosophila border cell migration as a model paradigm

The paper develops a computational model of Drosophila border cell migration that integrates intercellular forces and shape changes, validated with live imaging data, revealing new insights into migration dynamics in heterogeneous environments.

Threshold-dependent negative autoregulation of PIF4 gene expression optimizes growth and fitness in Arabidopsis

This study shows that PIF4 gene expression is negatively autoregulated, with a threshold-dependent mechanism that optimizes growth and fitness in Arabidopsis.

Hydrolysis-dependent severing tunes internal monomeric heterogeneity to shape actin length distributions

This study develops a computational model to show how cofilin-dependent severing and nucleotide state influence actin filament length distributions and structural heterogeneity.