Mohit Prasad

Modeling collective cell migration in a heterogeneous environment: Drosophila border cell migration as a model paradigm

The paper develops a computational model of Drosophila border cell migration that integrates intercellular forces and shape changes, validated with live imaging data, revealing new insights into migration dynamics in heterogeneous environments.

HSF1 Activator Azadiradione Ameliorates Parkinson Disease and Extends Lifespan in Preclinical Models: Analysis of Underlying Molecular Mechanism

This study shows that azadiradione enhances protein quality control mechanisms and alleviates Parkinson's disease symptoms in preclinical models.

Ecdysone Orchestrates Notch and Broad Symphony to Craft Epithelial Cell Shape Change

This study investigates how Ecdysone receptor (EcR) modulates epithelial cell shape change in Drosophila oogenesis by regulating the Notch-Broad axis and junction remodeling.

Germline protein, Cup, non-cell autonomously limits migratory cell fate in Drosophila oogenesis.

The paper shows that the germline protein Cup non-cell autonomously restricts JAK-STAT activation in Drosophila follicle cells, influencing border cell fate through Notch signaling.

TOR signalling regulates epithelial cell shape transition in Drosophila oogenesis

This study shows TOR signaling regulates epithelial cell shape transition in Drosophila oogenesis by modulating endocytosis and PAR-1-mediated removal of Fasciclin 2.