Bradford Clark Dickerson

Cerebrospinal fluid YWHAG:NPTX2 ratio predicts clinical severity and future phenoconversion in frontotemporal lobar degeneration

The paper identifies the CSF YWHAG:NPTX2 ratio as a biomarker for predicting clinical severity and phenoconversion in FTLD, showing strong correlation with disease progression and improved trial design potential.

Characterisation of Posterior Predominant Amyloid PET Binding Across Multiple Cohorts

This paper identifies a posterior predominant amyloid PET binding pattern in multiple cohorts, showing its clinical and biological relevance and suggesting the need for more nuanced analysis methods.

Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole-Genome Sequencing

This study identifies genetic risk factors for FTLD-TDP subtypes using whole-genome sequencing and meta-analysis across multiple cohorts.

Detecting Primary Progressive Aphasia (PPA) from Text: A Benchmarking Study

This study benchmarks machine learning models for classifying PPA subtypes from speech, finding that traditional classifiers with embeddings are competitive with transformer-based models.

Functional connectivity gradients as a common neural architecture for predictive processing in the human brain

The paper examines functional connectivity gradients in brain regions to explore their role in predictive processing, identifying two key gradients that align with hierarchical models of brain function.

Neural substrates of verbal repetition deficits in primary progressive aphasia

The paper investigates cortical thickness correlations with verbal repetition tasks in PPA patients, supporting phonological working memory theories and revealing subtype-specific atrophy patterns.

Altered functional connectivity of cortical networks in semantic variant Primary Progressive Aphasia

This study examines altered functional connectivity in brain networks of svPPA patients compared to controls, finding increased between-network connectivity and decreased within-network connectivity in the default mode network.

Preserved functional connectivity in the default mode and salience networks is associated with youthful memory in superaging

This study finds that preserved functional connectivity in default mode and salience networks in superagers correlates with better memory performance compared to typical older adults.

Evidence for a Large-Scale Brain System Supporting Allostasis and Interoception in Humans

The paper identifies a large-scale brain system in humans associated with interoception and allostasis using functional MRI and a predictive model.