Author

Florence Cordier

Centre National de la Recherche ScientifiqueORCID 0000-0002-5963-7773Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A Ulliana· 1 shared Ahmed HaouziD· 1 shared Ayten DizkırıcıiD· 1 shared Carine DerviauxiD· 1 shared Clément MadruiD· 1 shared Elsa D. GarciniD· 1 shared F TorresiD· 1 shared Ghislaine HennekeiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A Ulliana

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2 papers

Recent·Most cited

Engineering SIRPα conformational plasticity to reveal a cryptic pocket suitable for structure-based drug design

Martin Storder, Sarah Barelier, Florence Cordier, Taher Yacoub, Laura Ilari, Karine Barral, S Mahmoodi, Magalí Sáez‐Ayala, Sébastien Combes, S. Betzi, Carine Derviaux, A Ulliana, F Torres, J Rubin, Philippe Roche, , TW Miller

This paper identifies a cryptic pocket in SIRPα that can be targeted for drug design by engineering conformational changes to expose it.

bioRxiv · Dec 23, 2025 · PreprintBiochemistry

Communication between DNA polymerases and Replication Protein A within the archaeal replisome

Markel Martínez‐Carranza, Léa Vialle, Clément Madru, Florence Cordier, Ayten Dizkırıcı, Ahmed Haouz, Pierre Legrand, Rémy A. Le Meur, Patrick England, Rémi Dulermo, J. Iñaki Guijarro, Ghislaine Henneke, Ludovic Sauguet

This study reveals how archaeal RPA's winged-helix domain interacts with DNA primase and polymerase, enhancing PriSL activity and providing insights into replication regulation.

Nature Communications · Dec 30, 2024Peer-reviewedMolecular Biology