Author

Graeme W. Howe

Queen's UniversityORCID 0000-0002-5976-0739Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

George Colin diCenzoiD· 2 shared Nicholas T. SmithiD· 2 shared Amir R. Bunyat‐zadaiD· 1 shared Autumn J. HodginsiD· 1 shared Avena C. RossiD· 1 shared Chantelle J. CapicciottiiD· 1 shared Emily H. Perrino· 1 shared Esther R. HoffmaniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiochemistry

George Colin diCenzoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Evolution and remodeling of acceptor specificity in the NodZ α-1,6-fucosyltransferase

Nicholas T. Smith, George Colin diCenzo, Graeme W. Howe

This study investigates the evolution of acceptor specificity in NodZ fucosyltransferases, identifying key residues and evolutionary changes that influence substrate preference.

bioRxiv · Oct 6, 2026 · PreprintBiochemistry

Characterization of a novel fatty acid-modifying pathway toward the biosynthesis of tambjamine BE-18591 in Streptomyces

Neil L. Grenade, Yan Feng, Emily H. Perrino, Avena C. Ross, Graeme W. Howe

This study characterizes four novel Streptomyces proteins involved in the biosynthesis of the alkylamine component of the tambjamine BE-18591, revealing distinct biosynthetic mechanisms compared to Proteobacteria.

Journal of Natural Products · Nov 5, 2025Peer-reviewedBiochemistry

Characterization of bacterial fucokinase/GDP-fucose pyrophosphorylase (FKP) enzymes supports the evolution of interdomain communication and modularity in the FKP family

Nicholas T. Smith, Autumn J. Hodgins, Marie E. Boddington, Chantelle J. Capicciotti, George Colin diCenzo, Graeme W. Howe

This study characterizes bacterial FKP enzymes, revealing evolutionary origins and functional diversity through biochemical and phylogenetic analyses.

bioRxiv · Aug 5, 2025 · PreprintBiochemistry

Genome mining leads to the identification of a stable and promiscuous Baeyer-Villiger monooxygenase from a thermophilic microorganism

Amir R. Bunyat‐zada, Stephan E. Ducharme, Maria E. Cleveland, Esther R. Hoffman, Graeme W. Howe

The paper identifies a stable and promiscuous Baeyer-Villiger monooxygenase from a thermophilic microorganism and demonstrates its potential as an industrial biocatalyst.

ChemBioChem · Jul 11, 2024Peer-reviewedBiochemistry