Author

Alexandria L. Sohn

Frederick National Laboratory for Cancer ResearchORCID 0000-0002-5976-6620Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Andrew G. StepheniD· 1 shared Caroline J. DeHartiD· 1 shared Daniel A. Ritt· 1 shared David DurrantiD· 1 shared Deborah K. MorrisoniD· 1 shared Dominic EspositoiD· 1 shared Dwight V. NissleyiD· 1 shared Felice C. LightstoneiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Andrew G. StephenORCID

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1 paper

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedSep 15, 2025

An In Vitro BRAF Activation Assay Elucidates Molecular Mechanisms Driving the Disassembly of the Autoinhibited BRAF State

Daniel A. Ritt, David Durrant, Matthew R. Drew…·Deborah K. Morrison

This study develops an in vitro BRAF activation assay to elucidate molecular mechanisms of BRAF disassembly and identifies RAS binding as critical for activation.

9 citations

experimental assay