Author

Miguel Á. Japón

Instituto de Biomedicina de SevillaORCID 0000-0002-5980-5044Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Alejandro Belmonte‐FernándeziD· 2 shared Carmen SáeziD· 2 shared Francisco RomeroiD· 2 shared Joaquín Herrero‐RuiziD· 2 shared Mar Mora‐SantosiD· 2 shared M. Cristina Limón‐MortésiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

Alejandro Belmonte‐FernándezORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Overexpression of betaTrCP1 elicits cell death in cisplatin-induced senescent cells

Alejandro Belmonte‐Fernández, Joaquín Herrero‐Ruiz, M. Cristina Limón‐Mortés, Carmen Sáez, Miguel Á. Japón, Mar Mora‐Santos, Francisco Romero

This study shows that overexpressing betaTrCP1 causes death of cisplatin-induced senescent cells by promoting proteasomal degradation of p21 CIP1 through NPM1 retention in nucleoli.

Cell Death and Disease · Mar 25, 2025Peer-reviewedCell Biology

βTrCP is involved in the localization of the MRN complex on chromatin to enhance DNA damage repair

Alejandro Belmonte‐Fernández, Joaquín Herrero‐Ruiz, Carmen Sáez, Miguel Á. Japón, Mar Mora‐Santos, Francisco Romero

This study shows βTrCP interacts with the MRN complex and enhances its recruitment to chromatin, improving DNA damage repair.

bioRxiv · Mar 6, 2025 · PreprintCell Biology