Overexpression of betaTrCP1 elicits cell death in cisplatin-induced senescent cells
Alejandro Belmonte‐Fernández, Joaquín Herrero‐Ruiz, M. Cristina Limón‐Mortés, Carmen Sáez, Miguel Á. Japón, Mar Mora‐Santos, Francisco Romero
This study shows that overexpressing betaTrCP1 causes death of cisplatin-induced senescent cells by promoting proteasomal degradation of p21 CIP1 through NPM1 retention in nucleoli.
Cell Death and Disease · Mar 25, 2025Peer-reviewedCell Biology