hSpindly's dynamic controls SAC activity independently of the KBB pathway at unattached kinetochores
Mar Mora‐Santos, Joaquín Herrero‐Ruiz, Dirk Fennema Galparsoro, Alejandro Belmonte‐Fernández, Nuria Ferrándiz, Francisco Romero
This study identifies hSpindly as a dynamic modulator of SAC activity via the RZZ pathway, independent of the KBB pathway, and highlights its role in drug resistance.
bioRxiv · Jul 25, 2025 · PreprintCell Biology