Trifluoroacetate reduces plasma lipid levels and the development of atherosclerosis in mice
Wei Tang, Audrey S. Black, Romana Moench, Katayoon Marzban, Juan A. Raygoza Garay, James J. Zheng, Louis Patrick Conway, Antônio F. M. Pinto, Christopher G. Parker, Alan Saghatelian, Luke J. Leman, M. Reza Ghadiri
This study shows that trifluoroacetate reduces plasma lipids and atherosclerosis in mice by activating PPAR-alpha, but also highlights its environmental and clinical relevance.
bioRxiv · Mar 6, 2025 · PreprintBiochemistry