Author

Louis Patrick Conway

Scripps Research InstituteORCID 0000-0002-8448-5804Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Christopher G. ParkeriD· 2 shared Alan SaghatelianiD· 1 shared Anil VasudevaniD· 1 shared Antônio F. M. PintoiD· 1 shared Anurupa Shrestha· 1 shared Appaso Mahadev JadhaviD· 1 shared Audrey S. Black· 1 shared Christian M. ChaheineiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Christopher G. ParkerORCID

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2 papers

Recent·Most cited

Proteome-Wide Discovery of Degradable Proteins Using Bifunctional Molecules

Ines Forrest, Louis Patrick Conway, Clara Gathmann, Appaso Mahadev Jadhav, Tzu-Yuan Chiu, Christian M. Chaheine, Michelle A. Estrada, Anurupa Shrestha, Kathy Sarris, Justin M. Reitsma, Scott E. Warder, Anil Vasudevan, Shaun M. McLoughlin, Christopher G. Parker

The paper introduces AgnoTACs, bifunctional molecules that enable proteome-wide discovery of degradable proteins, identifying over 50 previously untargeted proteins.

ACS Central Science · Oct 21, 2025Peer-reviewedBiochemistry

Trifluoroacetate reduces plasma lipid levels and the development of atherosclerosis in mice

Wei Tang, Audrey S. Black, Romana Moench, Katayoon Marzban, Juan A. Raygoza Garay, James J. Zheng, Louis Patrick Conway, Antônio F. M. Pinto, Christopher G. Parker, Alan Saghatelian, Luke J. Leman, M. Reza Ghadiri

This study shows that trifluoroacetate reduces plasma lipids and atherosclerosis in mice by activating PPAR-alpha, but also highlights its environmental and clinical relevance.

bioRxiv · Mar 6, 2025 · PreprintBiochemistry