Modeling of hepatitis B virus infection spread in primary human hepatocytes
Zhenzhen Shi, Masataka Tsuge, Nicholson T. Collier, Yasue Takeuchi, Takuro Uchida, Carolyn M. Rutter, Yuji Teraoka, Susan L. Uprichard, Yuji Ishida, Chise Tateno, Jonathan Ozik, Harel Dahari, Kazuaki Chayama
The paper models HBV infection spread in primary human hepatocytes using agent-based modeling, identifying viral kinetic patterns and estimating the efficacy of an entry inhibitor.
Journal of Virology · Aug 4, 2025Peer-reviewedSystems Biology