Zhenzhen Shi

This paper develops an agent-based model to simulate HCV cell-to-cell spread in vitro, incorporating cell proliferation, size changes, and foci merging, and shows it fits experimental data well.

This study characterizes the multiphasic viral replication kinetics of rat HEV in vivo, showing liver as the main replication site and ribavirin's partial efficacy in preventing viral rebound.

The paper models HBV infection spread in primary human hepatocytes using agent-based modeling, identifying viral kinetic patterns and estimating the efficacy of an entry inhibitor.

The paper develops a stochastic agent-based model to explain multiphasic HBV kinetics in humanized mice by simulating intracellular virion production cycles.